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Table 3 Efficacy of diverse hormone receptor and androgen receptor status

From: Neoadjuvant pyrotinib plus trastuzumab and chemotherapy for HER2-positive breast cancer: a prospective cohort study

Characteristics

tpCR, n(%)

Non-tpCR, n(%)

χ2

P

bpCR, n(%)

Non-bpCR, n(%)

χ2

P

ER

 Positive (n = 63)

23(33.82)

40(57.14)

7.560

0.006

29(38.67)

34(53.97)

3.231

0.072

 Negative (n = 75)

45(66.18)

30(42.86)

46(61.33)

29(46.03)

PR

 Positive (n = 54)

18(26.47)

36(51.43)

9.021

0.003

22(29.33)

32(50.79)

6.620

0.010

 Negative (n = 84)

50(73.53)

34(48.57)

53(70.67)

31(49.21)

HR

 ER and/or PR positive (n = 69)

26(38.24)

43(61.43)

7.422

0.006

32(42.67)

37(58.73)

3.534

0.060

 ER and PR negative (n = 69)

42(61.76)

27(38.57)

43(57.33)

26(41.27)

AR

 Positive (n = 117)

53(77.94)

64(91.43)

4.863

0.027

59(78.67)

58(92.06)

4.763

0.029

 Negative (n = 21)

15(22.06)

6(8.57)

16(21.33)

5(7.94)

  1. tpCR total pathologic complete response, bpCR breast pathologic complete response. ER estrogen receptor; progesterone receptor, HR hormone receptor, AR androgen receptor