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Table 4 Univariable analysis and multivariable logistic regression of PPOI

From: Nomogram for predicting prolonged postoperative ileus after laparoscopic low anterior resection for rectal cancer

Variables

Univariate analysis

Multivariate analysis

OR (95% CI)

P value

OR (95% CI)

P value

Baseline characteristics

 Sex

  Female

Ref

   

  Male

1.331 (0.808–2.192)

0.261

  

 Age (years)

   < 65

Ref

   

   ≥ 65

2.060 (1.240–3.421)

0.005

1.816 (1.040–3.172)

0.036

 Smoking history

  Yes

1.128 (0.648–1.967)

0.670

  

  No

Ref

   

 Drinking history

  Yes

1.275 (0.634–2.560)

0.495

  

  No

Ref

   

 Hypertension

  Yes

1.062 (0.615–1.834)

0.829

  

  No

Ref

   

 Diabetes

  Yes

0.527 (0.204–1.362)

0.186

  

  No

Ref

   

 Respiratory disease

  Yes

0.811 (0.334–1.969)

0.643

  

  No

Ref

   

 Cardiac disease

  Yes

0.907 (0.309–2.659)

0.858

  

  No

Ref

   

 Previous abdominal surgery

  Yes

1.775 (0.997–3.158)

0.051

1.576 (0.836–6.309)

0.16

  No

Ref

   

 ASA score

  I

Ref

   

  II

1.044 (0.619–1.759)

0.873

  

  III

0.778 (0.262–2.306)

0.650

  

 Hypoproteinemia

  Yes

3.465 (1.742–6.893)

 < 0.001

2.565 (1.183–5.563)

0.017

  No

Ref

   

 Anemia

  Yes

1.748 (0.983–3.110)

0.057

1.322 (0.642–2.722)

0.449

  No

Ref

   

 Hypokalaemia

  Yes

2.333 (0.954–5.705)

0.063

2.361 (0.883–6.309)

0.087

  No

Ref

   

 Narrow pelvis

  Yes

1.624 (0.777–3.397)

0.198

  

  No

Ref

   

 Large MFA

  Yes

1.225 (0.722–2.077)

0.452

  

  No

Ref

   

 Body mass index (kg/m2)

   < 25

Ref

   

   ≥ 25

1.479 (0.900–2.431)

0.123

  

 Visceral obesity

  Yes

1.412 (0.822–2.426)

0.212

  

  No

Ref

   

 Sarcopenia

  Yes

1.491 (0.870–2.553)

0.146

  

  No

Ref

   

 Preoperative chemotherapy

  Yes

1.227 (0.553–2.725)

0.615

  

  No

Ref

   

 Preoperative radiotherapy

  Yes

1.400 (0.596–3.289)

0.440

  

  No

Ref

   

 Surgical difficulty

  High

3.492 (1.821–6.698)

 < 0.001

2.934 (1.406–6.121)

0.004

  Low

Ref

   

Intraoperative characteristics

 Surgery type

  Robotic-assisted

0.884 (0.534–1.464)

0.632

  

  Laparoscopic

Ref

   

 Diverting ileostomy

  Yes

0.709 (0.422–1.191)

0.194

  

  No

Ref

   

 Specimen extraction approaches

  Conventional extraction

Ref

   

  NOSES

1.242 (0.634–2.433)

0.527

  

 Operation time (min)

   < 180

Ref

   

   ≥ 180

1.773 (1.071–2.934)

0.026

1.427 (0.794–2.565)

0.234

 Estimated blood loss (ml)

   < 100

Ref

   

   ≥ 100

2.444 (1.206–4.956)

0.013

1.733 (0.779–3.855)

0.178

 Conversion

  Yes

3.441 (1.009–11.736)

0.048

3.853 (0.995–14.925)

0.051

  No

Ref

   

Pathological characteristics

 Tumor differentiation

  Poor

Ref

   

  Moderate

0.694 (0.341–1.412)

0.313

  

  High

0.818 (0.314–2.133)

0.681

  

 Tumor height

  Low

1.372 (0.828–2.273)

0.220

  

  Middle

Ref

   

 Tumor diameter (cm)

   ≤ 5

Ref

   

   > 5

1.649 (0.929–2.928)

0.088

0.864 (0.438–1.708)

0.675

 Tumor stage

  I

Ref

   

  II

0.974 (0.494–1.921)

0.939

  

  III

1.105 (0.555–2.200)

0.777

  

Postoperative characteristics

 Postoperative use of opioid analgesic

  Yes

2.849 (1.710–4.747)

 < 0.001

2.624 (1.513–4.553)

0.001

  No

Ref

   

 Postoperative transfusion

  Yes

2.333 (0.954–5.705)

0.063

1.406 (0.464–4.259)

0.547

  No

Ref

   
  1. ASA American Society of Anesthesiologists Classification, MFA rectal mesenteric fat, NOSES natural orifice specimen extraction surgery