Table 3 Association of TEG parameters with clinical parameters in patients with CRC
Variable | R | P (χ2) | K | P (χ2) | α-Angle | P (χ2) | MA | P (χ2) | ||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
LR (n, %) | HR (n, %) | LK (n, %) | HK (n, %) | Lα (n, %) | Hα (n, %) | LMA (n, %) | HMA (n, %) | |||||
Age (years) | ||||||||||||
 ≤ 65 | 23 (11.7) | 174 (88.3) | 0.719 (0.129) | 13 (6.6) | 184 (93.4) | 0.496 (0.463) | 166 (84.3) | 31 (15.7) | 0.273 (1.200) | 174 (88.3) | 23 (11.7) | 0.188 (1.735) |
 > 65 | 20 (10.5) | 170 (89.5) | 16 (8.4) | 174 (91.6) | 152 (80.0) | 38 (20.0) | 159 (83.7) | 31 (16.3) | ||||
Sex | ||||||||||||
 Male | 22 (9.5) | 210 (90.5) | 0.212 (1.555) | 13 (5.6) | 219 (94.4) | 0.084 (2.985) | 199 (85.8) | 33 (14.2) | 0.023 (5.139) | 207 (89.2) | 25 (10.8) | 0.027 (4.871) |
 Female | 21 (13.5) | 134 (86.5) | 16 (10.3) | 139 (89.7) | 119 (76.8) | 36 (23.2) | 126 (81.3) | 29 (18.7) | ||||
Preoperative CEA | ||||||||||||
 Normal | 30 (11.7) | 227 (88.3) | 0.770 (0.085) | 14 (5.4) | 243 (94.6) | 0.019 (5.490) | 226 (87.9) | 31 (12.1) | < 0.001 (20.236) | 236 (91.8) | 21 (8.2) | < 0.001 (24.130) |
 High | 13 (10.7) | 109 (89.3) | 15 (12.3) | 107 (87.7) | 84 (68.9) | 38 (31.1) | 89 (73.0) | 33 (27.0) | ||||
Preoperative CA19-9 | ||||||||||||
 Normal | 40 (12.4) | 282 (87.6) | 0.116 (2.468) | 21 (6.5) | 302 (93.5) | 0.043 (3.869) | 272 (84.2) | 51 (15.8) | 0.003 (8.057) | 291 (90.1) | 32 (9.9) | < 0.001 (32.554) |
 High | 3 (5.3) | 54 (94.7) | 8 (14.3) | 48 (85.7) | 38 (67.9) | 18 (32.1) | 34 (60.7) | 22 (39.3) | ||||
Tumor location | ||||||||||||
 Colon | 28 (11.9) | 208 (88.1) | 0.601 (0.274) | 25 (10.6) | 211 (89.4) | 0.004 (8.111) | 182 (77.1) | 54 (22.9) | 0.001 (11.244) | 186 (78.8) | 50 (21.2) | < 0.001 (28.065) |
 Rectum | 15 (10.1) | 133 (89.9) | 4 (2.7) | 144 (97.3) | 134 (90.5) | 14 (9.5) | 145 (98.0) | 3 (2.0) | ||||
Differentiation | ||||||||||||
 Poorly | 20 (15.7) | 107 (84.3) | 0.085 (2.961) | 15 (11.8) | 112 (88.2) | 0.060 (3.544) | 90 (70.9) | 37 (29.1) | < 0.001 (12.860) | 97 (76.4) | 30 (23.6) | < 0.001 (12.865) |
 Medium + well | 22 (9.6) | 207 (90.4) | 14 (6.1) | 215 (93.9) | 198 (86.5) | 31 (13.5) | 207 (90.4) | 22 (9.6) | ||||
Growth pattern | ||||||||||||
 Protuberant | 15 (12.7) | 103 (87.3) | 0.907 (0.014) | 8 (6.8) | 110 (93.2) | 0.462 (5.40) | 98 (83.1) | 20 (16.9) | 0.332 (0.942) | 106 (89.8) | 12 (10.2) | 0.080 (3.074) |
 Ulcerative/invasive | 27 (12.3) | 193 (87.7) | 20 (9.1) | 200 (90.9) | 173 (78.6) | 47 (21.4) | 182 (82.7) | 38 (17.3) | ||||
Vascular invasion | ||||||||||||
 Negative | 26 (11.5) | 200 (88.5) | 0.871 (0.026) | 9 (4.0) | 217 (96.0) | 0.001 (10.405) | 201 (88.9) | 25 (11.1) | < 0.001 (17.446) | 206 (91.2) | 20 (8.8) | 0.001 (10.854) |
 Positive | 17 (11.0) | 138 (89.0) | 20 (12.9) | 135 (87.1) | 112 (72.3) | 43 (27.7) | 123 (79.4) | 32 (20.6) | ||||
Nerve invasion | ||||||||||||
 Negative | 28 (10.7) | 233 (89.3) | 0.612 (0.258) | 18 (6.9) | 243 (93.1) | 0.438 (0.602) | 222 (85.1) | 39 (14.9) | 0.0290 (4.770) | 234 (89.7) | 27 (10.3) | 0.006 (7.673) |
 Positive | 15 (12.5) | 105 (87.5) | 11(9.2) | 109 (90.8) | 91 (75.8) | 29 (24.2) | 95 (79.2) | 25 (20.8) | ||||
Tumor status | ||||||||||||
 T1+2 | 10 (8.9) | 102 (91.1) | 0.377 (0.779) | 1 (0.9) | 111 (99.1) | 0.002 (9.952) | 109 (97.3) | 3 (2.7) | < 0.001 (24.822) | 112 (100.0) | 0 (0.0) | < 0.001 (25.663) |
 T3+4 | 33 (12.0) | 241 (88.0) | 28 (10.2) | 246 (89.8) | 208 (75.9) | 66 (24.1) | 220 (80.3) | 54 (19.7) | ||||
Nodal status | ||||||||||||
 N0 | 22 (9.4) | 211 (90.6) | 0.225 (1.472) | 7 (3.0) | 226 (97.0) | < 0.001 (16.454) | 213 (91.4) | 20 (8.6) | < 0.001 (31.590) | 221 (94.8) | 12 (5.2) | < 0.001 (34.726) |
 N1+2 | 20 (13.4) | 129 (86.6) | 21 (14.1) | 128 (85.9) | 103 (69.1) | 46 (30.9) | 110 (73.8) | 39 (26.2) | ||||
Metastasis status | ||||||||||||
 M0 | 35 (10.3) | 306 (89.7) | 0.188 (1.734) | 23 (6.7) | 318 (93.3) | 0.206 (1.601) | 292 (85.6) | 49 (14.4) | < 0.001 (22.071) | 307 (90.0) | 34 (10.0) | < 0.001 (35.834) |
 M1 | 7 (17.1) | 34 (82.9) | 5 (12.2) | 36 (87.8) | 23 (56.1) | 18 (43.9) | 23 (56.1) | 18 (43.9) | ||||
Disease stage | ||||||||||||
 I + II | 21 (9.3) | 205 (90.7) | 0.170 (1.881) | 8 (3.5) | 218 (96.5) | < 0.001 (12.387) | 207 (91.6) | 19 (8.4) | < 0.001 (33.297) | 215 (95.1) | 11 (4.9) | < 0.001 (37.708) |
 III + IV | 22 (13.8) | 138 (86.3) | 21 (13.1) | 139 (86.9) | 110 (68.8) | 50 (31.3) | 117 (73.1) | 43 (26.9) | ||||