From: Implication of perineural invasion in patients with stage II gastric cancer
Characteristics | Â | PNI | p value | |
---|---|---|---|---|
Absence (N = 133) | Presence (N = 100) |  | ||
Gender (%) | Female | 40 (30.08) | 35 (35) | 0.513 |
Male | 93 (69.92) | 65 (65) | Â | |
Age (mean ± SD, years) |  | 60.81 ± 11.94 | 56.69 ± 13.29 | 0.014 |
Age (%) |  < 60 years | 56 (42.11) | 55 (55.00) | 0.069 |
 ≥ 60 years | 77 (57.89) | 45 (45.00) |  | |
Tumor location (%) | Lower | 67 (50.38) | 53 (53) | 0.305 |
Middle | 18 (13.53) | 19 (19) | Â | |
Upper | 29 (21.80) | 13 (13) | Â | |
EGJ | 19 (14.29) | 15 (15) | Â | |
Type of gastrectomy (%) | Partial | 72 (54.14) | 52 (52) | 0.849 |
Total | 61 (45.86) | 48 (48) | Â | |
Adjuvant chemotherapy (%) | No | 44 (33.08) | 31 (31) | 0.845 |
Yes | 89 (66.92) | 69 (69) | Â | |
CEA (ng/ml) (%) |  ≤ 5 | 112 (84.21) | 87 (87) | 0.682 |
 > 5 | 21 (15.79) | 13 (13) |  | |
Vascular invasion (%) | Absence | 105 (78.95) | 78 (78) | 0.99 |
Presence | 28 (21.05) | 22 (22) | Â | |
Differentiation type (%) | Well differentiated | 46 (34.59) | 14 (14) |  < 0.001 |
Poorly differentiated | 87 (65.41) | 86 (86) | Â | |
Lauren classification (%) | Intestinal | 49 (36.84) | 16 (16) | 0.005 |
Diffuse | 44 (33.08) | 49 (49) | Â | |
Mix | 32 (24.06) | 28 (28) | Â | |
Others | 8 (6.02) | 7 (7) | Â | |
Tumor diameter (cm) (mean ± SD) |  | 4.02 ± 2.18 | 4.02 ± 2.13 | 0.999 |
Tumor diameter (cm) (%) |  ≤ 3 | 60 (45.11) | 41 (41) | 0.622 |
 > 3 | 73 (54.89) | 59 (59) |  | |
T Stage (%) | T1 | 9 (6.77) | 0 (0) |  < 0.001 |
T2 | 28 (21.05) | 5 (5) | Â | |
T3 | 95 (71.43) | 86 (86) | Â | |
T4a | 1 (0.75) | 9 (9) | Â | |
Lymph node metastasis (%) | Absence | 60 (45.11) | 59 (59) | 0.049 |
Presence | 73 (54.89) | 41 (41) | Â | |
TNM Stage (%) | IIA | 83 (62.41) | 52 (52) | 0.145 |
IIB | 50 (37.59) | 48 (48) | Â | |
Overall survival (%) | Alive | 107 (80.45) | 69 (69) | 0.063 |
Dead | 26 (19.55) | 31 (31) | Â | |
Disease-free survival (%) | No recurrence | 102 (76.69) | 66 (66) | 0.098 |
Recurrence or death | 31 (23.31) | 34 (34) | Â |