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Table 2 Clinical features of published cases of primary breast lymphoma in males

From: Clinicopathologic and mutational profiles of primary breast diffuse large B cell lymphoma in a male patient: case report and literature review

Case

Age(year)

Clinical manifestation

Location

Size (cm)

Sample type

Diagnosis

treatment

follow-up

References

1

76

A history of bilateral gynecomastia

Lower outer quadrant, right breast

7 × 6

mastectomy

DLBCL

CT

39 months, no recurrence

[3]

2

69

A soft, mobile, and clearly defined mass

Beneath the left nipple

2.4 × 3.9

mastectomy

DLBCL

CT

12 months, no recurrence

[4]

3

67

A palpable mass

Right breast

6 × 5

mastectomy

DLBCL

CT

12 months; died

[5]

4

64

A painless, gradually growing lump

Medial area, left breast

7 × 6

CNB

DLBCL

CT + RT

12 months, CR

[6]

5

62

A mass

Left breast

7 × 4

mastectomy

MZL

CT + RT

NA

[7]

6

48

A unilateral palpable well-circumscribed mass

Left breast

3.8 × 3.5

FNA

DLBCL

CT

7 months, reduction

[8]

7

51

A palpable mass for 3-month

Upper outer quadrant, left breast

2.3

mastectomy

ALCL

CT

12 months, no recurrence

[9]

8

50

Left gynecomastia

Behind the left nipple

2 × 2

CNB

DLBCL

CT

CR

[10]

9

46

A painless mass

Right chest wall

1.6

mastectomy

FL

NA

40 months; CR

[11]

10

75

A mass for 1 month

Under the left nipple

5

CNB

DLBCL

CT + RT

8 months; no recurrence

[12]

11

56

A visible tumor

Left breast

NA

CNB

DLBCL

CT + RT

17 months; CR

[13]

12

74

A mass

Right breast

NA

CNB

DLBCL

CT

CR

[14]

13

82

Bilateral painless masses

Bilateral breast

8 × 6

CNB

HGB

CT

CR

[15]

14

81

A painless tumor

Under the left nipple

5.5 × 5.0

CNB

DLBCL

CT + RT

CR

[16]

15

72

A progressive mass persisting over 3 months

Left breast

NA

NA

HGB

NA

NA

[17]

16

74

A mass

Right breast

NA

CNB

DLBCL

CT

CR

[18]

17

64

A gradually growing lump for 2 weeks

Upper outer quadrant, left breast

2.0 × 1.9

CNB

FL

CT + RT

CR

[19]

18

65

A gradually-increasing lump

The right chest

NA

Mastectomy

DLBCL

CT

5 years, CR

[20]

19

9

A mass for 2 months ago

Under the right areola

3.5 × 1.7

Mastectomy

B-LBL

NA

NA

[21]

20

64

A painful, enlarging lump for 1 month

Left breast lump

3.8

FNA

FL

NA

NA

[22]

21

63

A painless for 3 weeks

Right retro-areolar

5.4

CNB

DLBCL

CT

NA

[23]

  1. CNB Core needle biopsy, FNA Fine needle aspiration cytology, NA No available, HGB High-grade B cell lymphoma, CT Chemotherapy, RT Radiotherapy, MZL Marginal zone lymphoma, ALCL Anaplastic large-cell lymphoma, FL Follicular lymphoma, B-LBL B cell lymphoblastic lymphoma, CR Complete remission