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Table 4 CYP4B1 SNP–SNP interaction models analyzed by the MDR method

From: Missense variants in CYP4B1 associated with increased risk of lung cancer among Chinese Han population

Model

Training Bal. Acc

Testing Bal. Acc

OR (95% CI)

p value

CVC

rs2297810

0.537

0.537

1.38 (1.10 - 1.72)

0.0046

10/10

rs2297810,rs2297809

0.538

0.534

1.39 (1.11 - 1.73)

0.0039

7/10

rs2297810,rs4646491,rs2297809

0.538

0.532

1.39 (1.11 -1.73)

0.0039

10/10

  1. MDR Multifactor dimensionality reduction, Bal. Acc. Balanced accuracy, CVC Cross-validation consistency, OR Odds ratio, 95% CI 95% confidence interval.
  2. p values were calculated using χ2 tests; ‘p-value < 0.05’ and bold text represent statistical significance.