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Table 2 Univariable analysis and multivariate regression analysis of the 221 patients with IPNs after esophagectomy

From: Prediction of pulmonary metastasis in esophageal carcinoma patients with indeterminate pulmonary nodules

Multivariable analysis

Variable

Univariable Analysis P

Hazard ratio

p

Pathologic N category

 < 0.001

 

0.010

 0

 

Reference

 

 1

 

2.542

 

 2

 

6.805

 

 3

 

25.118

 

Number of IPNs

 < 0.001

 

 < 0.001

  < 3

 

Reference

 

  ≥ 3

 

27.180

 

Shape of the largest IPN

 < 0.001

 

0.008

 Round or round-like

 

8.949

 

 Others

 

Reference

 

Time of detection of IPNs(year)

 < 0.001

 

0.041

  < 1

 

Reference

 

 1–2

 

4.088

 

  > 2

 

4.388

 

Size of the largest IPN

 < 0.001

 

0.003

  < 5 mm

 

Reference

 

 5–10 mm

 

22.397

 

 10–30 mm

 

59.608

 

  > 30 mm

 

302.156

 

Mediastinal lymph node enlargement

 < 0.001

0.644

0.586

Density of the largest IPN

 < 0.001

1.975

0.336

Age

0.487

  

Gender

0.628

  

History of lung infection

0.337

  

Surgery approach

0.451

  

The range of lymph node dissection

0.406

  

Pathologic T category

0.422

  

Tumor differentiation

0.056

  

Location of the largest IPN

0.924

  

Area of the largest IPN

0.345

  

Calcification of the largest IPN

0.998

  
  1. IPN indeterminate pulmonary nodule