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Table 5 Univariable cox regression analyses for the development of metachronous peritoneal metastases after curative primary tumor resection

From: The impact of body weight on the development of peritoneal metastases in colorectal cancer patients: results from a nationwide cohort study

Variable

metachronous PM

Univariable Cox regression analysis

n (%)

HR

95% CI

p-value

Age (years)

278 (5.1)

0.991

0.979–1.003

0.146

Sex

   

0.450

 Male

156 (4.9)

Ref

Ref

 

 Female

122 (5.4)

1.096

0.864–1.388

 

Primary tumor location

   

0.189

 Right colon

107 (6.4)

1.286

0.981–1.685

 

 Left colon

106 (5.2)

Ref

Ref

 

 Rectum

65 (3.8)

1.155

0.846–1.576

 

Tumor differentiation

   

< 0.001

 Good/moderate

206 (4.7)

Ref

Ref

 

 Poor/undifferentiated

38 (8.7)

2.173

1.537–3.071

 

Tumor stage

   

< 0.001

 T0–2

20 (1.0)

Ref

Ref

 

 T3

152 (5.5)

5.852

3.674–9.328

 

 T4

106 (17.0)

18.822

11.672–30.354

 

Nodal stage

   

< 0.001

 N0

51 (2.0)

Ref

Ref

 

 N1

118 (6.5)

3.339

2.405–4.638

 

 N2

107 (11.0)

6.6412

4.593–8.952

 

Tumor histology

   

< 0.001

 Adenocarcinoma

233 (4.7)

Ref

Ref

 

 Mucinous adenocarcinoma

34 (8.2)

1.786

1.247–2.560

 

 Signet ring cell carcinoma

11 (24.4)

6.277

3.428–11.494

 

Weight category

   

0.376

 1. (BMI < 18.5); underweight

1 (1.1)

0.215

0.030–1.537

 

 2. (BMI 18.5–25); normal weight

107 (5.4)

Ref

Ref

 

 3. (BMI 25–30); overweight

117 (5.2)

0.913

0.703–1.187

 

 4. (BMI > 30); obesity

53 (4.8)

0.857

0.617–1.191

 

Synchronous systemic metastasis

   

< 0.001

 Yes

68 (15.9)

5.374

4.083–7.073

 

 No

210 (4.2)

Ref

Ref

 
  1. PM Peritoneal metastases, n Number, HR Hazard ratio, CI Confidence interval, BMI Body mass index (in kg/m2)