Table 4 Changes in R0 resection rates after neoadjuvant therapy
Study | N (AEG) | R0 resection rates | |||
|---|---|---|---|---|---|
Surgery alone | NACT | NACRT | P value | ||
FNCLCC [86] | 168 | 73% | 84% | Â | 0.04 |
MRC trial [87] | 206 | 76.4% | 75% | Â | / |
European Organisation [88] | 144 | 66.7% | 81.9% | Â | 0.036 |
Bosset study [89] | 297 | Â | Â | 81% | / |
101 | 95% | Â | 100% | / | |
Cross trial [32] | 275 | 69% |  | 92% |  < 0.001 |
Burmeister’s study [91] | 75 |  | 80.5% | 84.6% | 0.61 |
Nusrath’s study [92] | 70 |  | 86% | 88% | 1 |
Germany trial [93] | 126 | Â | 69.5% | 71.5% | / |