Table 2 Univariate analysis of clinicopathologic variables in relation to OS in patients with gallbladder cancer

Age (< 60, ≥ 60)

1.713

0.990-2.967

0.055

Gender (female, male)

1.008

0.628-1.619

0.972

T stage (T1/T2, T3/T4)

3.159

1.802-5.541

 < 0.001

N status (N0, N1/N2)

2.766

1.711-4.472

 < 0.001

TNM stage (I-II, III-IV)

3.061

1.945-4.817

 < 0.001

Differentiation (well or moderately, poorly or undifferentiated)

3.203

2.009-5.108

 < 0.001

Vascular invasion (positive, negative)

5.306

3.172-8.875

 < 0.001

Perineural invasion (positive, negative)

4.967

3.122-7.904

 < 0.001

NPS

 0

 1

1.983

0.891-4.417

0.094

 2

2.754

1.212-6.258

0.016