Table 1 Baseline characteristics of stage T3–4N0M0/T1–4N1–2M0 SCLC patients stratified by surgical treatment
Variables | No surgery n = 8572 | Surgery n = 342 | P |
|---|---|---|---|
Year of diagnosis | 0.198 | ||
2004–2009 | 4132 (48.20%) | 177 (51.75%) | |
2010–2015 | 4440 (51.80%) | 165 (48.25%) | |
Age | 0.794 | ||
< 65 years old | 3595 (41.94%) | 141 (41.23%) | |
≥ 65 years old | 4977 (58.06%) | 201 (58.77%) | |
Gender | 0.801 | ||
Male | 3976 (46.38%) | 161 (47.08%) | |
Female | 4596 (53.62%) | 181 (52.92%) | |
Race | 0.195 | ||
White | 7375 (86.04%) | 306 (89.47%) | |
Black | 790 (9.22%) | 24 (7.02%) | |
Other | 407 (4.75%) | 12 (3.51%) | |
Marital status | 0.01 | ||
Single | 1083 (12.63%) | 31 (9.06%) | |
Married | 4223 (49.27%) | 199 (58.19%) | |
Divorced/widowed/separated | 2955 (34.47%) | 100 (29.24%) | |
Unknown | 311 (3.63%) | 12 (3.51%) | |
Laterality | < 0.001 | ||
Right | 5136 (59.92%) | 174 (50.88%) | |
Left | 3436 (40.08%) | 168 (49.12%) | |
Primary site | < 0.001 | ||
Upper lobe | 4642 (54.15%) | 193 (56.43%) | |
Middle lobe | 392 (4.57%) | 19 (5.56%) | |
Lower lobe | 1725 (20.12%) | 112 (32.75%) | |
Other | 1813 (21.15%) | 18 (5.26%) | |
Combined small cell carcinoma | < 0.001 | ||
No/unknown | 8445 (98.52%) | 277 (80.99%) | |
Yes | 127 (1.48%) | 65 (19.01%) | |
Differentiation | < 0.001* | ||
Grade I/II | 36 (0.42%) | 12 (3.51%) | |
Grade III | 862 (10.06%) | 113 (33.04%) | |
Grade IV | 1752 (20.44%) | 111 (32.46%) | |
Unknown | 5922 (69.09%) | 106 (30.99%) | |
TNM stage | < 0.001 | ||
IIB | 890 (10.38%) | 167 (48.83%) | |
IIIA | 3883 (45.30%) | 139 (40.64%) | |
IIIB | 3799 (44.32%) | 36 (10.53%) | |
Radiotherapy | < 0.001 | ||
No/unknown | 2910 (33.95%) | 173 (50.58%) | |
Yes | 5662 (66.05%) | 169 (49.42%) | |
Chemotherapy | 0.012 | ||
No/unknown | 1749 (20.40%) | 89 (26.02%) | |
Yes | 6823 (79.60%) | 253 (73.98%) |