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Table 2 List of top 20 candidate hypermethylated/hypomethylated genes in adenomas

From: Screening and identifying of biomarkers in early colorectal cancer and adenoma based on genome-wide methylation profiles

Differentially hypermethylated CpG sites

Differentially hypomethylated CpG sites

CpG ID

Δβ

Chromosome

Gene name

Gene-based region

CpG island-based region

CpG ID

Δβ

Chromosome

Gene name

Gene-based region

CpG island-based region

cg09296001

0.702

7

SND1

Body

Island

cg01372366

− 0.518

11

PTPRJ

Body

Open sea

cg19358877

0.701

19

ZNF471

1stExon

Island

cg24032190

− 0.513

15

SMAD3

Body

Open sea

cg13895235

0.622

7

PRKAR1B

5′UTR

S_Shore

cg26668151

− 0.488

7

DNAJB6

Body

Open sea

cg22474464

0.617

20

NKX2-2

Body

Island

cg11228682

− 0.487

6

ATXN1

Body

Open sea

cg06952671

0.598

2

ITGA4

5′UTR

Island

cg14284630

− 0.483

11

OR5T3

TSS1500

Open sea

cg04292718

0.588

1

CD34

5′UTR

Island

cg06197966

− 0.481

10

SVIL

5′UTR

Open sea

cg25884711

0.652

7

NPY

5′UTR

Island

cg00438740

− 0.470

2

INPP5D

TSS200

N_Shore

cg22434409

0.579

4

KCNIP4

TSS1500

Island

cg02939767

− 0.459

20

TCF15

3′UTR

Open sea

cg12664464

0.578

20

GATA5

1stExon

Island

cg04923875

− 0.459

1

TNR

5′UTR

Open sea

cg16791424

0.575

14

NOVA1

TSS1500

S_Shore

cg02107844

− 0.453

15

SLCO3A1

Body

Open sea

cg16741041

0.575

13

SPG20

5′UTR

Island

cg03301058

− 0.452

6

GABRR2

Body

Open sea

cg05842348

0.565

14

PAX9

Body

S_Shore

cg13942186

− 0.452

9

EXD3

5′UTR

Open sea

cg03976877

0.563

7

VIPR2

1stExon

Island

cg03796321

− 0.452

15

AKAP13

Body

Open sea

cg25784220

0.562

19

ZSCAN18

1stExon

Island

cg06178383

− 0.451

16

SCNN1G

Body

Open sea

cg22065614

0.557

4

GLRB

1stExon

Island

cg27423177

− 0.448

12

C3AR1

TSS1500

Open sea

cg24152605

0.559

19

ZFP28

1stExon

Island

cg08942191

− 0.446

15

ARNT2

Body

Open sea

cg09248054

0.557

1

AGRN

Body

Island

cg23622047

− 0.438

2

RAPGEF4

Body

Open sea

cg24371075

0.553

17

MYH10

5′UTR

Island

cg00370106

− 0.437

6

SYTL3

1stExon

Open sea

cg14270292

0.550

6

EYA4

5′UTR

Island

cg24721964

− 0.433

3

CLRN1

TSS1500

Open sea

cg15139588

0.547

19

ZNF793

5′UTR

Island

cg01437515

− 0.427

1

TNFRSF4

Body

N_Shore