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Fig. 2 | World Journal of Surgical Oncology

Fig. 2

From: HSDL2 knockdown promotes the progression of cholangiocarcinoma by inhibiting ferroptosis through the P53/SLC7A11 axis

Fig. 2

HSDL2 knockdown enhances the proliferation, migration, and invasion of cholangiocarcinoma (CCA) cells. A–C The proliferation of RBE-sh#Ctrl, RBE-shHSDL2#1, RBE-shHSDL2#3, HCCC9810-Vector, and HCCC9810-HSDL2 cells was assessed by Cell Counting Kit-8 (A), 5-ethynyl-2′-deoxyuridine DNA synthesis (B), and colony formation (C) assays. D The migration of RBE-sh#Ctrl, RBE-shHSDL2#1, RBE-shHSDL2#3, HCCC9810-Vector, and HCCC9810-HSDL2 cells was evaluated using the Transwell migration assays. E The invasion of RBE-sh#Ctrl, RBE-shHSDL2#1, RBE-shHSDL2#3, HCCC9810-Vector, and HCCC9810-HSDL2 was assessed using Matrigel invasion assays. Data are presented as mean ± SD (n=3). *p < 0.05, **p < 0.01, and ***p < 0.001

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World Journal of Surgical Oncology

ISSN: 1477-7819

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