Table 3 Clinicopathological factors of PDAC patients with tumor tissues (n = 33) and the association with CXCR4 expression in stroma (n = 33)

Age (years)

64.8 ± 1.7

 − 0.353^a

0.08

Overall survival (OS, months)

21.0 ± 3.2

 − 0.055^a

0.76

Disease-free survival (DFS, months)

18.2 ± 3.3

 − 0.133^a

0.46

Gender

n (%)

M ± SEM

 Male

16 (48.5)

20.0 ± 4.7

0.84

 Female

17 (51.5)

31.2 ± 9.2

T status

 T1/T2

29 (87.9)

25.9 ± 5.9

0.73

 T3/T4

4 (12.1)

25.0 ± 10.4

N status

 N0

13 (39.4)

35.4 ± 9.8

0.09

 N1

14 (42.4)

25.7 ± 7.2

 N2

6 (18.2)

5.0 ± 5.0

M status

 No

33 (100.0)

25.8 ± 5.3

-

TNM stage

 I/IIA

12 (36.4)

34.2 ± 10.3

0.23

 IIB/III

21 (63.6)

21.0 ± 5.8

Tumor differentiation

 Well/moderate

24 (72.7)

19.2 ± 5.3

0.05^*

 Poor

9 (27.3)

43.3 ± 11.5

Tumor location

 Head

23 (69.7)

30.0 ± 6.7

0.18

 Body or tail

10 (30.3)

16.0 ± 7.3

Vascular Invasion

 Absent

21 (63.6)

24.8 ± 6.8

0.77

 Present

12 (36.4)

27.5 ± 8.5

Lymphatic invasion

 Absent

20 (60.6)

24.0 ± 6.7

0.68

 Present

13 (39.4)

28.5 ± 8.8

Neural invasion

 Absent

6 (18.2)

36.7 ± 15.8

0.48

 Present

27 (81.8)

23.3 ± 5.4

Local recurrence

 Absent

26 (78.8)

30.0 ± 6.3

0.22

 Present

7 (21.2)

10.0 ± 4.4

Distant metastasis

 Absent

18 (54.5)

22.2 ± 6.4

0.44

 Present

15 (45.5)

30.0 ± 8.8

Exitus

 No

15 (45.5)

20.0 ± 7.4

0.15

 Yes

18 (54.5)

30.6 ± 7.4