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Table 2 Baseline information of the patients in the ESD and surgery groups

From: Comparison of endoscopic submucosal dissection versus surgery for early gastric cancer in the elderly: a pooled analysis

Characteristics

Studies

Participants (ESD/ Surgery)

Odds Ratio/Mean Difference (95% CI)

Heterogeneity

Age

8

1017/1317

0.24 [-0.06, 0.53]; P = 0.12

I2 = 90.26%; P = 0.00

Sex (male)

8

1017/1317

1.12 [0.93, 1.36]; P = 0.24

I2 = 0.00%; P = 0.97

ASA (≥ 3)

2

479/473

0.65 [0.27, 1.56]; P = 0.34

I2 = 44.81%; P = 0.18

ECOG (≥ 2)

2

479/473

0.33 [0.17, 0.65]; P = 0.00*

I2 = 59.69%; P = 0.12

Hypertension

3

352/503

0.77 [0.58, 1.03]; P = 0.08

I2 = 0.00%; P = 0.53

DM

4

401/547

0.79 [0.53, 1.18]; P = 0.25

I2 = 0.00%; P = 0.94

CD

4

401/547

0.66 [0.43, 1.01]; P = 0.06

I2 = 0.00%; P = 0.69

CKD

2

181/176

0.46 [0.18, 1.18]; P = 0.11

I2 = 0.00%; P = 0.91

Liver dysfunction

3

269/415

0.80 [0.35, 1.82]; P = 0.60

I2 = 0.00%; P = 0.58

Tumor size

7

885/1185

-0.93 [-1.92, 0.06]; P = 0.06

I2 = 98.82%; P = 0.00

Location

6

   

Upper

 

187/293

1.03 [0.80, 1.33]; P = 0.80

I2 = 0.00%; P = 0.67

Middle

 

240/361

0.87 [0.66, 1.16]; P = 0.36

I2 = 26.58%; P = 0.24

Lower

 

468/589

reference

reference

Histology (diff/undiff)

8

1017/1317

1.92 [0.95, 3.86]; P = 0.07

I2 = 83.56%; P = 0.00

Invasion depth (M/SM)

5

753/920

2.85 [0.59, 13.75]; P = 0.19

I2 = 96.07%; P = 0.00

  1. Abbreviations: ESD Endoscopic submucosal dissection, ASA American Society of Anesthesiologists, ECOG Eastern Cooperative Oncology Groupprevious, DM Diabetes mellitus, CD Cardiovascular disease, CKD Chronic kidney disease, M Mucosa, SM Submucosa