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Table 2 Evaluation of publication bias and sensitivity analysis

From: Efficacy of sequential TACE on primary hepatocellular carcinoma with microvascular invasion after radical resection: a systematic review and meta-analysis

Index

Egger’s regression

Duval and Tweedie’s trim and fill

Intercept

p

Original effect size

Studies trimmed

Adjusted effect size

1-year RFS

1.465

0.232

1.31 (1.24, 1.39)

4

1.27 (1.19, 1.35)

2-year RFS

 − 1.127

0.494

1.42 (1.29, 1.54)

1

1.40 (1.28, 1.53)

3-year RFS

2.348

0.074

1.58 (1.41, 1.75)

0

1.58 (1.41, 1.75)

5-year RFS

3.688

0.061

1.47 (1.16, 1.78)

0

1.47 (1.16, 1.78)

1-year OS

2.486

0.196

1.14 (1.07, 1.21)

5

1.08 (1.01, 1.14)

2-year OS

1.319

0.265

1.26 (1.19, 1.33)

2

1.24 (1.17, 1.31)

3-year OS

3.728

0.012

1.33 (1.19, 1.47)

3

1.22 (1.05, 1.39)

5-year OS

3.875

0.007

1.36 (1.19, 1.54)

4

1.21 (1.04, 1.39)

  1. Abbreviation: RFS Recurrence-free survival, OS Overall survival