Table 1 Clinicopathological data of patients with high grade rectal neuroendocrine neoplasms
Clinicopathological character | Total n = 85 | |
|---|---|---|
n | IQR or % | |
Sex, n (%) | ||
Female | 35 | 41.2% |
Male | 50 | 58.8% |
Age, year (IQRa) | 57.0 | (52.0–66.0) |
Tumor size, cm (IQR) | 3.0 | (2.0–5.5) |
Distance from the anus, cm (IQR) | 6.0 | (4.0–10.0) |
Ki-67, % (IQR) | 60.0 | (40.0–80.0) |
T stage, n (%) | ||
T1 | 12 | 14.1% |
T2 | 18 | 21.2% |
T3 | 36 | 42.4% |
T4 | 19 | 22.4% |
Lymph node metastasis, n (%)b | ||
Negative | 22 | 34.9% |
Positive | 41 | 65.1% |
Evaluate lymph nodes, n (IQR)b | 14.0 | (6.0–17.0) |
Positive lymph nodes, n (IQR)b | 1.0 | (0.0–5.0) |
LNR, (IQR)b | 0.07 | (0.00–0.44) |
Distant metastasis, n (%) | ||
Negative | 65 | 76.5% |
Positive | 20 | 23.5% |
Neoadjuvant therapy, n (%) | ||
No | 78 | 91.8% |
Yes | 7 | 8.2% |
Surgical type, n (%) | ||
Only biopsy | 9 | 10.6% |
Local excision | 13 | 15.3% |
Radical resection | 52 | 61.2% |
Palliative surgery | 11 | 12.9% |
Adjuvant therapy, n (%) | ||
No | 44 | 51.8% |
Platinum-based regimen | 25 | 29.4% |
Other chemotherapy | 16 | 18.8% |
Microvascular invasion, n (%) | ||
Negative | 69 | 81.2% |
Positive | 16 | 18.8% |
Perineural invasion, n (%) | ||
Negative | 71 | 83.5% |
Positive | 14 | 16.5% |