Table 2 Subgroup analysis of circulating miRNA in diagnosis of benign or malignant pulmonary nodules
From: Meta analysis of the diagnostic value of circulating miRNA in benign and malignant pulmonary nodules
Classification | Studies (n) | Sensitivity (95%CI) | Specificity (95%CI) | PLR (95%CI) | NLR (95%CI) | DOR (95%CI) | AUC (95%CI) |
|---|---|---|---|---|---|---|---|
Ethnicity: | |||||||
 Asian | 12 | 0.78(0.68,0.86) | 0.83(0.78,0.87) | 4.6(3.6,5.9) | 0.27(0.18,0.39) | 17(11,29) | 0.86(0.83,0.89) |
 Non-Asian | 5 | 0.88(0.78,0.94) | 0.85(0.74,0.92) | 5.8(3.3,10.2) | 0.14(0.07,0.27) | 42(16,105) | 0.93(0.90,0.95) |
miRNA source: | |||||||
 Plasma | 12 | 0.81(0.73,0.86) | 0.82(0.76,0.87) | 4.5(3.5,5.9) | 0.24(0.17,0.32) | 19(13,28) | 0.88(0.85,0.91) |
 Serum | 5 | 0.83(0.60,0.94) | 0.87(0.79,0.93) | 6.6(3.8,11.5) | 0.19(0.07,0.52) | 34(9,129) | 0.91(0.88,0.93) |