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Fig. 2 | World Journal of Surgical Oncology

Fig. 2

From: Four calcium signaling pathway-related genes were upregulated in microcystic adnexal carcinoma: transcriptome analysis and immunohistochemical validation

Fig. 2

Gene expression changes in microcystic adnexal carcinoma. Five patients without metastasis and five controls qualified for RNA sequencing. A Heatmap shows the differentially expressed genes between MAC and normal skin tissues. B, C KEGG and GO analysis of the differentially expressed genes. D Heatmap of expression of the 4 key genes. Abbreviations: MAC, microcystic adnexal carcinoma tissue; N, normal skin tissue; KEGG, Kyoto Encyclopedia of Genes and Genomes; GO, Gene Ontology; CACNA1S, calcium voltage-gated channel subunit alpha 1S; MYLK3, myosin light chain kinase 3; RYR1, ryanodine receptor 1; ATP2A1, ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1

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