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Table 4 Factors associated with the risk of metachronous liver metastasis for stage III pancreatic cancer (univariate and multivariate cox regression model) (N = 707)

From: Risk factors of liver metastasis from advanced pancreatic adenocarcinoma: a large multicenter cohort study

Variable

Univariate analysis

Stepwise multivariate analysis

HR

95% CI

P value

HR

95% CI

P value

Age (≥60 vs. <60)

0.78

0.60–1.02

0.0736

0.77

0.58–1.01

0.0555

Sex (male vs. female)

0.82

0.63–1.08

0.1534

   

Smoking (yes vs. no)

0.98

0.75–1.29

0.8878

   

Alcohol (yes vs. no)

0.93

0.63–1.39

0.7288

   

Location (body/tail vs. head/neck)

0.81

0.62–1.07

0.1367

   

Diameter (≥20 vs. <20)

1.62

1.02–2.59

0.0413

1.58

0.99–2.52

0.0542

ALT or AST (elevated vs. normal)

1.02

0.67–1.55

0.9162

   

ALB (low vs. normal)

1.03

0.72–1.47

0.8848

   

CA19-9 (elevated vs. normal)

1.15

0.81–1.62

0.4381

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