Taurolidine group n = 60 | Control group n = 60 | p | |||
---|---|---|---|---|---|
Age (years) | 66.9 (26.4–87.1) | 64.5 (22.8–80.8) | 0.08 | ||
Sex (male/female) | 37 (61.7%)/23 (38.3%) | 35 (58.3%)/25 (41.7%) | - | ||
Height | 170 (7.7) | 171 (8.8) | 0.76 | ||
Weight | 74.2 (13.7) | 74.2 (11.8) | 0.92 | ||
Type of cancer | n = 60 | n = 60 | |||
Colon | 48.3% | 29 | 46.7% | 28 | |
Gastric | 43.3% | 26 | 43.3% | 26 | |
Pancreatic | 8.3% | 5 | 10% | 6 | |
UICC histopathological staging | |||||
Colon cancer | 29 | 28 | |||
I | 8 | 9 | |||
II | 8 | 9 | |||
III | 13 | 10 | |||
Gastric cancer | 26 | 26 | |||
IA | 4 | 5 | |||
IB | 6 | 7 | |||
II | 8 | 5 | |||
IIIA | 5 | 6 | |||
IIIB | 3 | 3 | |||
Pancreatic cancer | 5 | 6 | |||
I | 2 | ||||
II | 2 | 2 | |||
III | 3 | 2 | |||
ASA classification (all patients) | |||||
I | 23.3% | 14 | 23.3% | 14 | |
II | 38.3% | 23 | 38.3% | 23 | |
III | 38.3% | 23 | 38.3% | 23 | |
Risk factors | 32 | 24 | |||
Arterial hypertension | 33.3% | 20 | 26.6% | 16 | |
Chronic obstructive lung disease | 1.6% | 1 | 5% | 3 | |
Diabetes mellitus | 13.3% | 8 | 6.6% | 4 | |
Nephropathy | 5% | 3 | 1.6% | 1 | |
Tumour location | |||||
Colon: | |||||
Caecum | 1 | ||||
Ascending colon | 5 | 3 | |||
Transverse colon | 3 | 6 | |||
Descending colon | 2 | 3 | |||
Sigmoid colon | 5 | 5 | |||
Rectum | 14 | 10 | |||
Stomach: | |||||
Gastric cardia | 5 | 3 | |||
Gastric fundus | 4 | 6 | |||
Gastric body | 6 | 9 | |||
Gastric antrum | 11 | 8 | |||
Pancreas: | |||||
Pancreatic head | 5 | 6 | |||
Intervention | |||||
Right colectomy | 4 | 4 | |||
Extended right colectomy | 2 | 1 | |||
Left colectomy | 2 | 6 | |||
Extended left colectomy | 1 | 2 | |||
Sigmoidectomy | 5 | 4 | |||
Rectum resection | 10 | 9 | |||
Abdominoperineal resection | 4 | 1 | |||
Subtotal colectomy | 1 | 1 | |||
Total gastrectomy | 14 | 19 | |||
Total gastrectomy + splenectomy | 3 | 2 | |||
Subtotal (3/4) gastrectomy | 8 | 5 | |||
Distal esophageal resection | 1 | ||||
Pancreatic head resection (Kausch-Whipple' resection) | 1 | 3 | |||
Pylorus-preserving duodenopancreatectomy | 4 | 3 |