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Table 1 Proposed approach for defining risk of aggressive behavior in GIST, by Fletcher [2]

From: Surgical resection for gastrointestinal stromal tumors (GIST): experience on 25 patients

 

Tumor Size (cm)

Mitotic count

Very low risk

< 2 cm

< 5/50 HPF

Low risk

2–5 cm

< 5/50 HPF

Intermediate risk

< 5 cm

6–10/50 HPF

 

5–10 cm

< 5/50 HPF

High risk

> 5 cm

> 5/50 HPF

 

> 10 cm

any mitotic rate

 

any size

> 10/50 HPF