Figure 5
From: Aberrant E-cadherin staining patterns in invasive mammary carcinoma
Invasive lobular carcinoma with glandular "ductal" differentiation (case 5). A: Moderately differentiated invasive "ductal" carcinoma and carcinoma in situ on core biopsy (Hematoxylin and eosin, right) showing complete absence of E-cadherin immunoreactivity. (Immunoperoxidase stain for E-cadherin, left). B: No immunoreactivity for E-cadherin (Immunoperoxidase stain for E-cadherin, left) confirms invasive lobular carcinoma with glandular differentiation in the excision biopsy (Hematoxylin and eosin, right). C: Invasive lobular carcinoma with gland formation (Hematoxylin and eosin, right and immunoperoxidase stain for E-cadherin, left).