Hepatocytes | Bile duct epithelium | |
---|---|---|
Arrangement | Singly, 2-dimensional small to large clusters, trabeculae of 2 to 3 cells layer thick | Picket fences with nuclear palisading, monolayered honeycomb sheets |
Cells | Polygonal to round | Cuboidal to columnar |
Cytoplasm | Abundant dense granular* to vacuolated (lipid/glycogen), pigments (lipofusin, bile, or hemosiderin) | Scant, pale |
Nuclei | ||
Round, centrally located, intranuclear cytoplasmic inclusions, nuclear clearing binucleation | Uniform, small, round, more condensed chromatin | |
Nucleoli | Prominent | Inconspicuous |