Figure 1From: Prostate stem cell antigen (PSCA) expression in human prostate cancer tissues and its potential role in prostate carcinogenesis and progression of prostate cancerRepresentatives of PSCA IHC and ISH staining in Pca (A. IHC staining, B. ISH staining, ×200 magnification). A1, B1: negative control of IHC and ISH. PBS replacing the primary antibody (A1) and hybridization with a sense PSCA probe (B1) showed no background staining. A2, B2: a moderately differentiated Pca (Gleason score = 3+3 = 6) with moderate staining (composite score = 6) in all malignant cells; A2: IHC shows not only cell surface but also apparent cytoplasmic staining of PSCA protein. A3, B3: a poorly differentiated Pca (Gleason score = 4+4 = 8) with very strong staining (composite score = 9) in all malignant cells.Back to article page