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Table 4 Overall survival analysis by the Cox proportional hazards regression model in 146 cases of IDC-NOS

From: Prognostic value of poorly differentiated clusters in invasive breast cancer

    Variable

Univariate

Multivariate

Hazard ratio

95% confidence interval

P

Hazard ratio

95% confidence interval

P

Age 40 or younger/>40

0.410

0.193 to 0.869

0.020*

0.622

0.279 to 1.388

0.246

T stage: T1/T2/T3

2.956

1.513 to 5.775

0.002*

4.064

1.839 to 8.982

0.001*

N stage: N0/N1/N2 or 3

2.890

1.848 to 4.519

<0.001*

3.482

1.185 to 10.234

0.023*

Lymphovascular invasion: negative/positive

3.841

1.909 to 7.729

<0.001*

0.516

0.106 to 2.507

0.412

Grade: G1/G2/G3

1.698

0.880 to 3.276

0.114

  

Not assessed

Estrogen receptor or progesterone receptor: negative/positive

0.922

0.460 to 1.849

0.819

  

Not assessed

HER-2: negative/positive

2.577

1.172 to 5.668

0.019*

0.874

0.357 to 2.136

0.767

Triple negative status: no/yes

1.393

0.670 to 2.895

0.375

  

Not assessed

Poorly differentiate cluster grade: G1/G2/G3

4.987

2.681 to 9.276

<0.001*

3.730

1.718 to 8.101

0.001*

Tumor budding: G1/G2/G3

2.285

1.442 to 3.623

<0.001*

1.517

0.597 to 2.564

0.120

  1. *P <0.05.