Positive surgical margins in nephron-sparing surgery: risk factors and therapeutic consequences

Table 1 Published hazard ratios (HR) for positive surgical margins in nephron-sparing surgery

Reference number	Number of cases	HR (recurrence)	HR (OS)	HR (CSS)
[5]	PSM: 22	Not reported	Not reported	Not significant
[5]	NSM: 100	Not reported	Not reported	Not significant
[68]	PSM: 14	Not reported	Not reported	3.45 (95% CI: 1.79-6.67)
[68]	NSM: 1787	Not reported	Not reported
[67]	PSM: 13	Not reported	Not reported	2.08 (95% CI: 0.84-5.17)
[67]	NSM: 155	Not reported	Not reported
[59]	PSM: 71	Not reported	1.1 (95% CI: 0.66-1.94)	Not significant
[59]	NSM: 587	Not reported		Not significant
[66]	PSM: 21	18.4 (95% CI: 2.27-110.8)	Not reported	Not reported
[66]	NSM: 922		Not reported	Not reported
[57]	PSM: 77	1 (95% CI: 0.23-4.3)	Not reported	Not reported
[57]	NSM: 1313		Not reported	Not reported
[35]	PSM: 12	11.5 (95% CI: 4.66-45.1)	Not reported	Not reported
[35]	NSM: 768		Not reported	Not reported
[56]	PSM: 101	Not significant	Not significant	Not significant
	NSM: 102

CI, confidence interval; CSS, cancer-specific survival; HR, hazard ratio; NSM, negative surgical margins; OS, overall survival; PSM, positive surgical margins.

ISSN: 1477-7819