Anaesthesia in patients undergoing cytoreductive surgery with hyperthermic intraperitoneal chemotherapy: retrospective analysis of a single centre three-year experience

Table 1 Patient characteristics, primary cancer, and intraperitoneal chemotherapy

Age; years	52 (20–72)
Gender; Male:Female	23:34
Weight; kg / Height; cm	70 (44–112) / 168 (155–185)
BMI; kg m⁻²	25 (16–41)
ASA class I/II/III	5/49/3
Comorbidities ¹
Cardiovascular	14
Pulmonary	5
Renal	4
Endocrine	3
Neurological	4
Obesity (BMI >30)	8
Medication
Single ß-blocking agent	2
Single ACE-inhibitor/AT2-blocker	3
Single diuretic	0
Combination of at least two drugs	6
Other drugs²	27
None	23
Origin of primary cancer
Appendix	33
Ovary	1
Colorectal	13
Mesothelioma	5
Gastric	1
Other origin³	4

54 patients underwent 57 procedures. Data are expressed as median (range) and numbers.
ACE, angiotensin converting enzyme; ASA, American Society of Anesthesiology; AT2, angiotensin II; BMI, body mass index (kg m⁻²).
¹Comorbidities: cardiovascular (arterial hypertension, cardiac valve pathology, hyperlipidemia); pulmonary (chronic bronchitis, asthma, obstructive sleep apnea syndrome, history of acute respiratory distress syndrome, history of pulmonary embolism); renal (one sided kidney agenesia, history of carcinoma of the kidney, incidentaloma, chronic kidney disease); endocrine (previous ovariectomy, medically treated hypothyroidism, diabetes mellitus); neurological (polyneuropathy, paraesthesia, migraine, herniated vertebral disc with neurological symptoms).
²Twenty seven patients were on additional medication: analgesics (n = 9), proton pump inhibitors (n = 6), vitamins and supplements (n = 5), laxatives (n = 5), hormone replacement therapy (n = 5), sedatives (n = 3), oral antidiabetics (n = 1), chemotherapeutic agents (n = 1), antidepressants (n = 1), antidiarrheals (n = 1), antiemetics (n = 1), acetylsalicylic acid (n = 1), statins (n = 1), calcium channel blocker (n = 1), herbal and homeopathic preparations (n = 2).
³Other origin summarizes endometrioid cancer (n = 2), cancer of the small intestine (n = 1) and urachus cancer (n = 1).

ISSN: 1477-7819