Overexpression of HSPA2 is correlated with poor prognosis in esophageal squamous cell carcinoma

Table 3 Multivariate survival analysis of overall survival and disease-free survival in 120 patients with ESCC

Features	Overall survival		Disease-free survival
	Hazard ratio (95% CI)	P value	Hazard ratio (95% CI)	P value
Primary tumor (T3 + T4/T1 + T2)	1.746 (1.104 to 2.762)	0.017^a	1.516 (1.005 to 2.289)	0.048^a
TNM stage (III/I + II)	16.347 (8.560 to 31.215)	<0.001^a	11.729 (6.448 to 21.335)	<0.001^a
Lymph node metastases (−/+)	0.838 (0.534 to 1.315)	0.442	0.906 (0.596 to 1.375)	0.642
HSPA2 expression (positive/negative)	2.210 (1.101 to 4.435)	0.026^a	2.115 (1.222 to 3.661)	0.007^a

^aP values considered statistically significant at <0.05. CI, confidence interval; ESCC, esophageal squamous cell carcinoma; G, grade; N, lymph node metastases; T, primary tumor.

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