Tumor-derived hepatocyte growth factor is associated with poor prognosis of patients with glioma and influences the chemosensitivity of glioma cell line to cisplatin in vitro

Table 1 Correlation among HGF expression, cell proliferation, IMD value and clinicopathological parameters of patients with gliomas

Variable	HGF expression^a		Cell proliferation^a		IMD value^b(mean ± SD)
	Low exp. (n = 31)	High exp. (n = 45)	Low PI (n = 33)	High PI (n = 43)
Histological grade
High grade (n = 41)	10	31	3	38	24.78 ± 10.30
Low grade (n = 35)	21	14	30	52	19.57 ± 8.62
	P = 0.001		P = 0.001		P = 0.021
Tumor recurrence
No (n = 57)	27	30	26	31	21.70 ± 9.83
Yes (n = 19)	4	15	76	12	24.42 ± 9.89
	P = 0.002		P = 0.323		P = 0.301
HGF expression
Low expression (n = 31)			24	7	18.24 ± 6.41
High expression (n = 45)			9	36	25.23 ± 10.82
			P = 0.001		P = 0.001
Cell proliferation
Low PI (n = 33)	24	9			19.31 ± 8.32
High PI (n = 43)	7	36			24.73 ± 10.37
	P = 0.001				P = 0.016

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